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dinB [2018-03-18 13:30:07]
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dinB [2018-03-18 13:30:07]

nuclease inhibitor
locus
BSU05630
pI
5.61
mw
19.76 kDa
protein length
172 aa Sequence Blast
gene length
516 bp Sequence Blast
function
response to DNA damage
product
nuclease inhibitor
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

    • Gene

    Coordinates
    608,246 → 608,764

    The protein

    Protein family

  • dinB family (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]
    description
    [Pubmed|1847907]

    regulatory mechanism

  • [protein|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA]: repression, [PubMed|8226626,8969214], in [regulon|D267AF38B0CF107042326E9B8F3DD3C9C85840E4|LexA regulon]

    • regulation

  • induced by DNA damage ([protein|search|LexA]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8226626,8969214 PubMed]

    • additional information

  • the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
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    Biological materials

    Mutant

  • BKE05630 (Δ[gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT, downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA
  • BKK05630 (Δ[gene|DEB7605B4F6F5F365A49C1C15647F9767B01BF66|bstG]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05630 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTAAAATTCCCCCTTT, downstream forward: _UP4_TAAAAAAGCGGCTCCCTAAA

    • References

  • 12884008,1847907,8226626,8969214,9555905,16267290